Metronidazole conjugated magnetic nanoparticles loaded with amphotericin B exhibited potent effects against pathogenic Acanthamoeba castellanii belonging to the T4 genotype

Metronidazole conjugated magnetic nanoparticles loaded with amphotericin B exhibited potent effects against pathogenic Acanthamoeba castellanii belonging to the T4 genotype

Abstract Acanthamoeba castellanii can cause granulomatous amoebic encephalitis and Acanthamoeba keratitis. Currently, no single drug has been developed to effectively treat infections caused by Acanthamoeba. Recent studies have shown that drugs conjugated with nanoparticles exhibit potent in vitro a...

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Bibliographic Details
Main Authors: Sumayah Abdelnasir, Ayaz Anwar, Muhammad Kawish, Areeba Anwar, Muhammad Raza Shah, Ruqaiyyah Siddiqui, Naveed Ahmed Khan
Format: Article
Language:English
Published: SpringerOpen 2020-07-01
Series:AMB Express
Subjects:
Magnetic nanoparticles
Metronidazole
Amphotericin B
Acanthamoeba
Online Access:http://link.springer.com/article/10.1186/s13568-020-01061-z

Internet

http://link.springer.com/article/10.1186/s13568-020-01061-z

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