Significant Differences in Host-Pathogen Interactions Between Murine and Human Whole Blood

Significant Differences in Host-Pathogen Interactions Between Murine and Human Whole Blood

Murine infection models are widely used to study systemic candidiasis caused by C. albicans. Whole-blood models can help to elucidate host-pathogens interactions and have been used for several Candida species in human blood. We adapted the human whole-blood model to murine blood. Unlike human blood,...

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Bibliographic Details
Main Authors: Silke Machata, Sravya Sreekantapuram, Kerstin Hünniger, Oliver Kurzai, Christine Dunker, Katja Schubert, Wibke Krüger, Bianca Schulze-Richter, Cornelia Speth, Günter Rambach, Ilse D. Jacobsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
whole blood ex vivo model
host-pathogen interaction
Candida albicans
neutrophils
mice
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.565869/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.565869/full

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