The cytoprotective effect of different doses of Sildenafil on indomethacin-induced gastric mucosal damage in rats:

Background: Sildenafil, a selective phosphodiesterase -5 (PDE-5) inhibitor increases cyclic guanosine monophosphate (cGMP) and amplifies many biological actions of nitric oxide (NO) which is an important mediator of gastric mucosal defense ; was evaluated in this study using different doses for its...

Full description

Bibliographic Details
Main Authors: Samir Y. N. Matloub, Mohammed J. Manna
Format: Article
Language:English
Published: Faculty of Medicine University of Baghdad 2011-01-01
Series:مجلة كلية الطب
Subjects:
Online Access:http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/950