Natural Docosahexaenoic Acid in the Triglyceride Form Attenuates In Vitro Microglial Activation and Ameliorates Autoimmune Encephalomyelitis in Mice

Natural Docosahexaenoic Acid in the Triglyceride Form Attenuates In Vitro Microglial Activation and Ameliorates Autoimmune Encephalomyelitis in Mice

Many neurodegenerative diseases are associated, at least in part, to an inflammatory process in which microglia plays a major role. The effect of the triglyceride form of the omega-3 polyunsaturated fatty acid docosahexaenoic acid (TG-DHA) was assayed in vitro and in vivo to assess the protective an...

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Bibliographic Details
Main Authors: Pilar Mancera, Blanca Wappenhans, Begoña Cordobilla, Noemí Virgili, Marco Pugliese, Fèlix Rueda, Juan F. Espinosa-Parrilla, Joan C. Domingo
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Nutrients
Subjects:
docosahexaenoic acid
microglia
omega-3 polyunsaturated fatty acid
oxidative stress
anti-inflammatory process
EAE model
Online Access:http://www.mdpi.com/2072-6643/9/7/681

Internet

http://www.mdpi.com/2072-6643/9/7/681

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