The Different Roles of hRAD50 in Microsatellite Stable and Unstable Colorectal Cancers

RAD50 protein is essential for DNA double-strand break repair and maintaining genomic integrity. In this study, we investigated the clinicopathological significance of hRAD50 expression and mutation in microsatellite stable (MSS) and unstable (MSI) colorectal cancers (CRCs). hRAD50 expression was ex...

Full description

Bibliographic Details
Main Authors: Jingfang Gao, Hong Zhang, Gunnar Arbman, Xiao-Feng Sun
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2008/724796