Novel apigenin based small molecule that targets snake venom metalloproteases.

The classical antivenom therapy has appreciably reduced snakebite mortality rate and thus is the only savior drug available. Unfortunately, it considerably fails to shield the viper bite complications like hemorrhage, local tissue degradation and necrosis responsible for severe morbidity. Moreover,...

Full description

Bibliographic Details
Main Authors: Venkatachalaiah Srinivasa, Mahalingam S Sundaram, Sebastian Anusha, Mahadevappa Hemshekhar, Siddaiah Chandra Nayaka, Kempaiah Kemparaju, Basappa, Kesturu S Girish, Kanchugarakoppal S Rangappa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153592?pdf=render