Lessons learned from the blockade of immune checkpoints in cancer immunotherapy

Abstract The advent of immunotherapy, especially checkpoint inhibitor-based immunotherapy, has provided novel and powerful weapons against cancer. Because only a subset of cancer patients exhibit durable responses, further exploration of the mechanisms underlying the resistance to immunotherapy in t...

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Bibliographic Details
Main Authors: Xiaolei Li, Changshun Shao, Yufang Shi, Weidong Han
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13045-018-0578-4