Zika virus induces neuronal and vascular degeneration in developing mouse retina

Zika virus induces neuronal and vascular degeneration in developing mouse retina

Abstract Zika virus (ZIKV), a mosquito-borne flavivirus, can cause severe eye disease and even blindness in newborns. However, ZIKV-induced retinal lesions have not been studied in a comprehensive way, mechanisms of ZIKV-induced retinal abnormalities are unknown, and no therapeutic intervention is a...

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Bibliographic Details
Main Authors: Yi Li, Shuizhen Shi, Fan Xia, Chao Shan, Yonju Ha, Jing Zou, Awadalkareem Adam, Ming Zhang, Tian Wang, Hua Liu, Pei-Yong Shi, Wenbo Zhang
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Acta Neuropathologica Communications
Subjects:
Zika virus
Retina
Neuronal degeneration
Vascular degeneration
Inflammation
Endoplasmic reticulum stress
Online Access:https://doi.org/10.1186/s40478-021-01195-6

Internet

https://doi.org/10.1186/s40478-021-01195-6

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