CpG Oligonucleotides as Cancer Vaccine Adjuvants

Adjuvants improve host responsiveness to co-delivered vaccines through a variety of mechanisms. Agents that trigger cells expressing Toll-like receptors (TLR) activate an innate immune response that enhances the induction of vaccine-specific immunity. When administered in combination with vaccines d...

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Bibliographic Details
Main Authors: Hidekazu Shirota, Debra Tross, Dennis M. Klinman
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Vaccines
Subjects:
CpG
TLR
Online Access:http://www.mdpi.com/2076-393X/3/2/390