Induction of interferon signaling and allograft inflammatory factor 1 in macrophages in a mouse model of breast cancer metastases [version 1; peer review: 2 approved, 1 approved with reservations]

Background: Metastatic breast cancer cells recruit macrophages (metastasis-associated macrophages, or MAMs) to facilitate their seeding, survival and outgrowth. However, a comprehensive understanding of the gene expression program in MAMs and how this program contributes to metastasis remain elusive...

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Bibliographic Details
Main Authors: Wei Zheng, Dejian Zhao, Hui Zhang, Prameladevi Chinnasamy, Nicholas Sibinga, Jeffrey W. Pollard
Format: Article
Language:English
Published: Wellcome 2021-03-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/6-52/v1