Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors

Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors

Acute myeloid leukemia (AML) is among the top four malignancies in Saudi nationals, and it is the top leukemia subtype worldwide. Resistance to available AML drugs requires the identification of new targets and agents. Hsp90 is one of the emerging important targets in AML, which has a central role i...

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Bibliographic Details
Main Authors: Ashraf N. Abdalla, Mohamed E. Abdallah, Akhmed Aslam, Ammar Bader, Antonio Vassallo, Nunziatina De Tommasi, Waleed H. Malki, Ahmed M. Gouda, Mohammed H. Mukhtar, Mahmoud Zaki El-Readi, Hamad M. Alkahtani, Alaa A.-M. Abdel-Aziz, Adel S. El-Azab
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
acute myeloid leukemia (AML), Hsp90
cyclin-dependent kinases (CDK), dinaciclib
Online Access:https://www.mdpi.com/1420-3049/25/9/2220

Internet

https://www.mdpi.com/1420-3049/25/9/2220

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