Bare bones pattern formation: a core regulatory network in varying geometries reproduces major features of vertebrate limb development and evolution.

<h4>Background</h4>Major unresolved questions regarding vertebrate limb development concern how the numbers of skeletal elements along the proximodistal (P-D) and anteroposterior (A-P) axes are determined and how the shape of a growing limb affects skeletal element formation. There is cu...

Full description

Bibliographic Details
Main Authors: Jianfeng Zhu, Yong-Tao Zhang, Mark S Alber, Stuart A Newman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20531940/pdf/?tool=EBI