Modelling Blood Flow and Metabolism in the Preclinical Neonatal Brain during and Following Hypoxic-Ischaemia.

Hypoxia-ischaemia (HI) is a major cause of neonatal brain injury, often leading to long-term damage or death. In order to improve understanding and test new treatments, piglets are used as preclinical models for human neonates. We have extended an earlier computational model of piglet cerebral physi...

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Bibliographic Details
Main Authors: Matthew Caldwell, Tracy Moroz, Tharindi Hapuarachchi, Alan Bainbridge, Nicola J Robertson, Chris E Cooper, Ilias Tachtsidis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4596480?pdf=render