Maternal Resveratrol Therapy Protects Male Rat Offspring against Programmed Hypertension Induced by TCDD and Dexamethasone Exposures: Is It Relevant to Aryl Hydrocarbon Receptor?

Maternal Resveratrol Therapy Protects Male Rat Offspring against Programmed Hypertension Induced by TCDD and Dexamethasone Exposures: Is It Relevant to Aryl Hydrocarbon Receptor?

Hypertension can originate from early-life adverse environmental in utero exposure to dexamethasone (DEX) or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Since DEX and TCDD are related to the aryl hydrocarbon receptor (AHR) signaling pathway, we examined whether resveratrol, an AHR modulator and anti...

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Bibliographic Details
Main Authors: Chien-Ning Hsu, Yu-Ju Lin, Pei-Chen Lu, You-Lin Tain
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
aryl hydrocarbon receptor
developmental origins of health and disease (DOHaD)
hypertension
nitric oxide
oxidative stress
TCDD
Online Access:http://www.mdpi.com/1422-0067/19/8/2459

Internet

http://www.mdpi.com/1422-0067/19/8/2459

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