Cloning and Expression of Recombinant Human Endostatin in Periplasm of Escherichia coli Expression System

Cloning and Expression of Recombinant Human Endostatin in Periplasm of Escherichia coli Expression System

Purpose: Recombinant human endostatin (rhEs) is an angiogenesis inhibitor which is used as a specific drug in the treatment of non-small-cell lung cancer. In the current research, we developed an efficient method for expressing soluble form of the rhEs protein in the periplasmic space of Escherichia...

Full description

Bibliographic Details
Main Authors: Abbas Mohajeri, Yones Pilehvar-Soltanahmadi, Mohammad Pourhassan-Moghaddam, Jalal Abdolalizadeh, Pouran Karimi, Nosratollah Zarghami
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2016-06-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Angiogenesis
Endostatin
Signal peptide
E. coli
Gene expression
Periplasm
Online Access:http://journals.tbzmed.ac.ir/APB/Manuscript/APB-6-187.pdf

Internet

http://journals.tbzmed.ac.ir/APB/Manuscript/APB-6-187.pdf

Similar Items