Inhibitory Receptors and Checkpoints in Human NK Cells, Implications for the Immunotherapy of Cancer

Inhibitory Receptors and Checkpoints in Human NK Cells, Implications for the Immunotherapy of Cancer

The highly destructive mechanisms by which the immune system faces microbial infections is under the control of a series of inhibitory receptors. While most of these receptors prevent unwanted/excessive responses of individual effector cells, others play a more general role in immunity, acting as tr...

Full description

Bibliographic Details
Main Authors: Simona Sivori, Mariella Della Chiesa, Simona Carlomagno, Linda Quatrini, Enrico Munari, Paola Vacca, Nicola Tumino, Francesca Romana Mariotti, Maria Cristina Mingari, Daniela Pende, Lorenzo Moretta
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
natural killer cells
inhibitory NK receptors
immune checkpoints
tumor immunotherapy
tumor escape
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02156/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02156/full

Similar Items