Neutrophil Extracellular Traps are Involved in the Innate Immune Response to Infection with Leptospira.

Neutrophil Extracellular Traps are Involved in the Innate Immune Response to Infection with Leptospira.

NETosis is a process by which neutrophils extrude their DNA together with bactericidal proteins that trap and/or kill pathogens. In the present study, we evaluated the ability of Leptospira spp. to induce NETosis using human ex vivo and murine in vivo models. Microscopy and fluorometric studies show...

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Bibliographic Details
Main Authors: Emilia Scharrig, Agostina Carestia, María F Ferrer, Maia Cédola, Gabriela Pretre, Ricardo Drut, Mathieu Picardeau, Mirta Schattner, Ricardo M Gómez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4498591?pdf=render

Internet

http://europepmc.org/articles/PMC4498591?pdf=render

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