Oxidized LDL upregulates macrophage DPP4 expression via TLR4/TRIF/CD36 pathwaysResearch in context

Background: We and others have shown that dipeptidyl peptidase-IV (DPP4) expression is increased in obesity/atherosclerosis and is positively correlated with atherosclerotic burden. However, the mechanism by which DPP4 expression is regulated in obesity remains unclear. In this study, we investigate...

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Bibliographic Details
Main Authors: Xiaoquan Rao, Shi Zhao, Zachary Braunstein, Hong Mao, Michael Razavi, Lihua Duan, Yingying Wei, Amelia C. Toomey, Sanjay Rajagopalan, Jixin Zhong
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419300714