ZEB Proteins in Leukemia: Friends, Foes, or Friendly Foes?

Abstract. ZEB1 and ZEB2 play pivotal roles in solid cancer metastasis by allowing cancer cells to invade and disseminate through the transcriptional regulation of epithelial-to-mesenchymal transition. ZEB expression is also associated with the acquisition of cancer stem cell properties and therapy r...

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Bibliographic Details
Main Authors: Bieke Soen, Niels Vandamme, Geert Berx, Jürg Schwaller, Pieter Van Vlierberghe, Steven Goossens
Format: Article
Language:English
Published: Wolters Kluwer 2018-06-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000043