Cationic amino acid transporter-2 regulates immunity by modulating arginase activity.

Cationic amino acid transporter-2 regulates immunity by modulating arginase activity.

Cationic amino acid transporters (CAT) are important regulators of NOS2 and ARG1 activity because they regulate L-arginine availability. However, their role in the development of Th1/Th2 effector functions following infection has not been investigated. Here we dissect the function of CAT2 by studyin...

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Bibliographic Details
Main Authors: Robert W Thompson, John T Pesce, Thirumalai Ramalingam, Mark S Wilson, Sandy White, Allen W Cheever, Stacy M Ricklefs, Stephen F Porcella, Lili Li, Lesley G Ellies, Thomas A Wynn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2265428?pdf=render

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http://europepmc.org/articles/PMC2265428?pdf=render

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