Control region mutations and the 'common deletion' are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma

<p>Abstract</p> <p>Background</p> <p>North central China has some of the highest rates of esophageal squamous cell carcinoma in the world with cumulative mortality surpassing 20%. Mitochondrial DNA (mtDNA) accumulates more mutations than nuclear DNA and because of its h...

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Bibliographic Details
Main Authors: Tang Ze-Zong, Hu Nan, McKenney Keith, Armistead David, Carrera Ana, Huppi Konrad, Abnet Christian C, Taylor Philip R, Dawsey Sanford M
Format: Article
Language:English
Published: BMC 2004-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/4/30