Biological Effects of Ciliary Neurotrophic Factor on hMADS Adipocytes

Biological Effects of Ciliary Neurotrophic Factor on hMADS Adipocytes

Administration of ciliary neurotrophic factor (CNTF) to experimental animals exerts anti-obesity effects by acting on multiple targets. In white adipose tissue CNTF reduces lipid content, promotes fatty acid (FA) oxidation and improves insulin sensitivity. This study was performed to establish wheth...

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Bibliographic Details
Main Authors: Jessica Perugini, Eleonora Di Mercurio, Giovanni Tossetta, Ilenia Severi, Federica Monaco, Marcella Reguzzoni, Marco Tomasetti, Christian Dani, Saverio Cinti, Antonio Giordano
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Endocrinology
Subjects:
ciliary neurotrophic factor
adipocytes
JAK STAT pathway
lipolysis
mitochondria
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00768/full

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https://www.frontiersin.org/article/10.3389/fendo.2019.00768/full

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