Dopamine receptor activation increases HIV entry into primary human macrophages.

Macrophages are the primary cell type infected with HIV in the central nervous system, and infection of these cells is a major component in the development of neuropathogenesis and HIV-associated neurocognitive disorders. Within the brains of drug abusers, macrophages are exposed to increased levels...

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Bibliographic Details
Main Authors: Peter J Gaskill, Hideaki H Yano, Ganjam V Kalpana, Jonathan A Javitch, Joan W Berman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182469?pdf=render