Genome-wide interrogation of Mammalian stem cell fate determinants by nested chromosome deletions.

Genome-wide interrogation of Mammalian stem cell fate determinants by nested chromosome deletions.

Understanding the function of important DNA elements in mammalian stem cell genomes would be enhanced by the availability of deletion collections in which segmental haploidies are precisely characterized. Using a modified Cre-loxP-based system, we now report the creation and characterization of a co...

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Main Authors: Simon Fortier, Mélanie Bilodeau, Tara Macrae, Jean-Philippe Laverdure, Valeria Azcoitia, Simon Girard, Jalila Chagraoui, Nancy Ringuette, Josée Hébert, Jana Krosl, Nadine Mayotte, Guy Sauvageau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3000362?pdf=render

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http://europepmc.org/articles/PMC3000362?pdf=render

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