The density of CD10 corresponds to commitment and progression in the human B lymphoid lineage.

BACKGROUND:Requirements for human B lymphopoiesis are still poorly understood, and that has hampered investigation of differentiation events. For example, there are few cell surface antigens that can be used as milestones of lineage progression. The CD10 ectoenzyme is one such marker and has been us...

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Bibliographic Details
Main Authors: Michiko Ichii, Kenji Oritani, Takafumi Yokota, Qingzhao Zhang, Karla P Garrett, Yuzuru Kanakura, Paul W Kincade
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2944886?pdf=render