Impact of the PSA-NCAM system on pathophysiology in a chronic rodent model of temporal lobe epilepsy

Polysialylation is a posttranslational modification of the neural cell adhesion molecule (NCAM). In the adult brain, polysialylated NCAM (PSA-NCAM) is restricted to regions of neurogenesis and neuroplasticity, where PSA promotes plastic changes. Because a variety of plastic changes including neuroge...

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Bibliographic Details
Main Authors: Anton Pekcec, Martina Mühlenhoff, Rita Gerardy-Schahn, Heidrun Potschka
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107000812