Adrenomedullin promotes differentiation of oligodendrocyte precursor cells into myelin-basic-protein expressing oligodendrocytes under pathological conditions in vitro

Oligodendrocytes, which are the main cell type in cerebral white matter, are generated from their precursor cells (oligodendrocyte precursor cells: OPCs). However, the differentiation from OPCs to oligodendrocytes is disturbed under stressed conditions. Therefore, drugs that can improve oligodendroc...

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Bibliographic Details
Main Authors: Takakuni Maki, Yoko Takahashi, Nobukazu Miyamoto, Anna C. Liang, Masafumi Ihara, Eng H. Lo, Ken Arai
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506115000586