The central role of nucleic acids in the pathogenesis of systemic lupus erythematosus [version 1; peer review: 3 approved]
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease whose pathogenesis can be conceptualized by a model based on a central role for immune complexes (ICs) between antinuclear antibodies and nucleic acids. According to this model, ICs can promote pathogenesis by two main mechanisms:...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2019-04-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-368/v1 |