Apoptosis in the Central Nervous System of Cerebral Adrenoleukodystrophy Patients

The childhood cerebral form of adrenoleukodystrophy (ALD) is a fatal demyelinating disease, yet mice deficient in the ALD gene do not show such clinicopathological phenotype. We have therefore investigated in human autopsy tissues whether the ALD gene mutation results in apoptosis of CNS cells. Spec...

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Bibliographic Details
Main Authors: Valérie Feigenbaum, Antoinette Gélot, Philippe Casanova, Catherine Daumas-Duport, Patrick Aubourg, Monique Dubois-Dalcq
Format: Article
Language:English
Published: Elsevier 2000-12-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996100903152