The primitive growth factor NME7AB induces mitochondrially active naïve-like pluripotent stem cells

Naïve pluripotent stem cells (PSCs) display a distinctive phenotype when compared to their “primed” counterparts, including, but not limited to, increased potency to differentiate and more robust mitochondrial respiration. The cultivation and maintenance of naïve PSCs have been notoriously challengi...

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Bibliographic Details
Main Authors: Carla O'Reilly, Qian Qi, Jennifer L. Peters, Yong Cheng, Sang-Oh Yoon, Min-Joon Han
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580818303327