Structure of reovirus sigma1 in complex with its receptor junctional adhesion molecule-A.

Viral attachment to specific host receptors is the first step in viral infection and serves an essential function in the selection of target cells. Mammalian reoviruses are highly useful experimental models for studies of viral pathogenesis and show promise as vectors for oncolytics and vaccines. Re...

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Bibliographic Details
Main Authors: Eva Kirchner, Kristen M Guglielmi, Holger M Strauss, Terence S Dermody, Thilo Stehle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2588538?pdf=render