Model-based assessment of mammalian cell metabolic functionalities using omics data

Model-based assessment of mammalian cell metabolic functionalities using omics data

Summary: Omics experiments are ubiquitous in biological studies, leading to a deluge of data. However, it is still challenging to connect changes in these data to changes in cell functions because of complex interdependencies between genes, proteins, and metabolites. Here, we present a framework all...

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Bibliographic Details
Main Authors: Anne Richelle, Benjamin P. Kellman, Alexander T. Wenzel, Austin W.T. Chiang, Tyler Reagan, Jahir M. Gutierrez, Chintan Joshi, Shangzhong Li, Joanne K. Liu, Helen Masson, Jooyong Lee, Zerong Li, Laurent Heirendt, Christophe Trefois, Edwin F. Juarez, Tyler Bath, David Borland, Jill P. Mesirov, Kimberly Robasky, Nathan E. Lewis
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports: Methods
Subjects:
metabolic function
omic data
systems biology
functional analysis
genome-scale metabolic network
transcriptomic
Online Access:http://www.sciencedirect.com/science/article/pii/S2667237521000850

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http://www.sciencedirect.com/science/article/pii/S2667237521000850

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