The SV40 late protein VP4 is a viroporin that forms pores to disrupt membranes for viral release.
Nonenveloped viruses are generally released by the timely lysis of the host cell by a poorly understood process. For the nonenveloped virus SV40, virions assemble in the nucleus and then must be released from the host cell without being encapsulated by cellular membranes. This process appears to inv...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-06-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3128117?pdf=render |