Hyperforin Promotes Post-stroke Neuroangiogenesis via Astrocytic IL-6-Mediated Negative Immune Regulation in the Ischemic Brain

Hyperforin Promotes Post-stroke Neuroangiogenesis via Astrocytic IL-6-Mediated Negative Immune Regulation in the Ischemic Brain

Hyperforin has been shown to be capable of promoting angiogenesis and functional recovery after ischemic stroke in our previous study. However, the exact mechanisms involved are not fully elucidated. In this study, adult male mice were subjected to 60-min transient middle cerebral artery occlusion f...

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Bibliographic Details
Main Authors: Hua Yao, Yujing Zhang, Huaqing Shu, Bing Xie, Yuanfa Tao, Yin Yuan, You Shang, Shiying Yuan, Jiancheng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
hyperforin
IL-6
immunity
ischemic stroke
neuroangiogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00201/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00201/full

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