Tumor lymphocyte immune response to preoperative radiotherapy in locally advanced rectal cancer: The LYMPHOREC study

Tumor lymphocyte immune response to preoperative radiotherapy in locally advanced rectal cancer: The LYMPHOREC study

Introduction: Some studies have suggested that baseline tumor-infiltrating-lymphocytes (TILs), such as CD8+ and FoxP3+ T-cells, may be associated with a better prognosis in colorectal cancer. We sought to investigate modulation of the immune response by preoperative radiotherapy (preopRT) and its im...

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Bibliographic Details
Main Authors: C. Mirjolet, C. Charon-Barra, S. Ladoire, F. Arbez-Gindre, A. Bertaut, F. Ghiringhelli, A. Leroux, D. Peiffert, C. Borg, J. F. Bosset, G. Créhange
Format: Article
Language:English
Published: Taylor & Francis Group 2018-03-01
Series:OncoImmunology
Subjects:
rectal cancer
radiation therapy
tumor-infiltrating lymphocytes
translational study
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1396402

Internet

http://dx.doi.org/10.1080/2162402X.2017.1396402

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