F-box protein specificity for g1 cyclins is dictated by subcellular localization.

Levels of G1 cyclins fluctuate in response to environmental cues and couple mitotic signaling to cell cycle entry. The G1 cyclin Cln3 is a key regulator of cell size and cell cycle entry in budding yeast. Cln3 degradation is essential for proper cell cycle control; however, the mechanisms that contr...

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Bibliographic Details
Main Authors: Benjamin D Landry, John P Doyle, David P Toczyski, Jennifer A Benanti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3405998?pdf=render