Source-Related Effects of Wastewater on Transcription Factor (AhR, CAR and PXR)-Mediated Induction of Gene Expression in Cultured Rat Hepatocytes and Their Association with the Prevalence of Antimicrobial-Resistant Escherichia coli.

Extracts of wastewater collected from 4 sewage treatment plants (STPs) receiving effluents from different sources in South India were investigated for their levels of transcription factor-mediated gene induction in primary cultured rat hepatocytes. In addition, the relation between gene induction le...

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Bibliographic Details
Main Authors: Keerthi S Guruge, Noriko Yamanaka, Miyuki Sonobe, Wataru Fujizono, Miyako Yoshioka, Masato Akiba, Takehisa Yamamoto, Derrick I Joshua, Keshava Balakrishna, Nobuyoshi Yamashita, Kurunthachalam Kannan, Toshiyuki Tsutsui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4575039?pdf=render