A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis.

<h4>Background</h4>Rheumatoid arthritis (RA) is a chronic autoimmune disorder affecting approximately 1% of the population. The disease results from the interplay between an individual's genetic background and unknown environmental triggers. Although human leukocyte antigens (HLAs)...

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Main Authors: Fina A S Kurreeman, Leonid Padyukov, Rute B Marques, Steven J Schrodi, Maria Seddighzadeh, Gerrie Stoeken-Rijsbergen, Annette H M van der Helm-van Mil, Cornelia F Allaart, Willem Verduyn, Jeanine Houwing-Duistermaat, Lars Alfredsson, Ann B Begovich, Lars Klareskog, Tom W J Huizinga, Rene E M Toes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-09-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.0040278