Endothelial Toxicity of High Glucose and its by-Products in Diabetic Kidney Disease

Alterations of renal endothelial cells play a crucial role in the initiation and progression of diabetic kidney disease. High glucose per se, as well as glucose by-products, induce endothelial dysfunction in both large vessels and the microvasculature. Toxic glucose by-products include advanced glyc...

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Bibliographic Details
Main Authors: Laetitia Dou, Noémie Jourde-Chiche
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/11/10/578