Effect of neoadjuvant chemotherapy on tumor-infiltrating lymphocytes and PD-L1 expression in breast cancer and its clinical significance

Effect of neoadjuvant chemotherapy on tumor-infiltrating lymphocytes and PD-L1 expression in breast cancer and its clinical significance

Abstract Background The effects of neoadjuvant chemotherapy on immune markers remain largely unknown. The specific aim of this study was to assess stromal tumor-infiltrating lymphocytes (TILs) and programmed death ligand 1 (PD-L1) protein expression in a cohort of breast cancer patients treated with...

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Bibliographic Details
Main Authors: Vasiliki Pelekanou, Daniel E. Carvajal-Hausdorf, Mehmet Altan, Brad Wasserman, Cristobal Carvajal-Hausdorf, Hallie Wimberly, Jason Brown, Donald Lannin, Lajos Pusztai, David L. Rimm
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Breast Cancer Research
Subjects:
Tumor infiltrating lymphocytes
Programmed death ligand 1
Neoadjuvant treatment
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s13058-017-0884-8

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http://link.springer.com/article/10.1186/s13058-017-0884-8

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