Safety and tracking of intrathecal allogeneic mesenchymal stem cell transplantation in healthy and diseased horses

Abstract Background It is currently unknown if the intrathecal administration of a high dose of allogeneic mesenchymal stem cells (MSCs) is safe, how MSCs migrate throughout the vertebral canal after intrathecal administration, and whether MSCs are able to home to a site of injury. The aims of the s...

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Bibliographic Details
Main Authors: Danielle Jaqueta Barberini, Monica Aleman, Fabio Aristizabal, Mathieu Spriet, Kaitlin C. Clark, Naomi J. Walker, Larry D. Galuppo, Rogério Martins Amorim, Kevin D. Woolard, Dori L. Borjesson
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-018-0849-6