UPR in palmitate-treated pancreatic beta-cells is not affected by altering oxidation of the fatty acid
<p>Abstract</p> <p>Background</p> <p>Elevated levels of lipids are detrimental for beta-cell function and mass. One of the mechanisms of how fatty acids induce apoptosis is development of the unfolded protein response (UPR). It is still far from understood how fatty aci...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-10-01
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| Series: | Nutrition & Metabolism |
| Subjects: | |
| Online Access: | http://www.nutritionandmetabolism.com/content/8/1/70 |