The Way to Ultrafast, High-Throughput Enantioseparations of Bioactive Compounds in Liquid and Supercritical Fluid Chromatography

Until less than 10 years ago, chiral separations were carried out with columns packed with 5 or 3 μ m fully porous particles (FPPs). Times to resolve enantiomeric mixtures were easily larger than 30 min, or so. Pushed especially by stringent requirements from medicinal and pharmaceutical...

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Bibliographic Details
Main Authors: Omar H. Ismail, Simona Felletti, Chiara De Luca, Luisa Pasti, Nicola Marchetti, Valentina Costa, Francesco Gasparrini, Alberto Cavazzini, Martina Catani
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/10/2709