Pluripotent stem cells secrete Activin A to improve their epiblast competency after injection into recipient embryos
Abstract It is not fully clear why there is a higher contribution of pluripotent stem cells (PSCs) to the chimera produced by injection of PSCs into 4-cell or 8-cell stage embryos compared with blastocyst injection. Here, we show that not only embryonic stem cells (ESCs) but also induced pluripotent...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2017-10-01
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Series: | Protein & Cell |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1007/s13238-017-0470-y |