Identification of miPEP133 as a novel tumor-suppressor microprotein encoded by miR-34a pri-miRNA

Identification of miPEP133 as a novel tumor-suppressor microprotein encoded by miR-34a pri-miRNA

Abstract Background Very few proteins encoded by the presumed non-coding RNA transcripts have been identified. Their cellular functions remain largely unknown. This study identifies the tumor-suppressor function of a novel microprotein encoded by the precursor of miR-34a. It consists of 133 amino ac...

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Bibliographic Details
Main Authors: Min Kang, Bo Tang, Jixi Li, Ziyan Zhou, Kang Liu, Rensheng Wang, Ziyan Jiang, Fangfang Bi, David Patrick, Dongin Kim, Anirban K. Mitra, Yang Yang-Hartwich
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Molecular Cancer
Subjects:
miPEP133
Tumor suppressor
miR-34a
Pri-miRNA-encoded protein
Nasopharyngeal carcinoma
Online Access:http://link.springer.com/article/10.1186/s12943-020-01248-9

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http://link.springer.com/article/10.1186/s12943-020-01248-9

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