Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation

Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation

Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have been widely associated to beneficial effect over different neurodegenerative diseases. In the present study, we tested the potential therapeutic effect of docohexanoic acid (DHA) and its hydroxylated derivate, DHAH, in a partial lesion model of Pa...

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Bibliographic Details
Main Authors: Sara Hernando, Catalina Requejo, Enara Herran, Jose Angel Ruiz-Ortega, Teresa Morera-Herreras, Jose Vicente Lafuente, Luisa Ugedo, Eusebio Gainza, Jose Luis Pedraz, Manoli Igartua, Rosa Maria Hernandez
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
6-OHDA
Polyunsaturated fatty acids
Docohexaenoic acid
Neuroprotection
Neuroinflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118302924

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http://www.sciencedirect.com/science/article/pii/S0969996118302924

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