Integrated proteomics identified up-regulated focal adhesion-mediated proteins in human squamous cell carcinoma in an orthotopic murine model.

Understanding the molecular mechanisms of oral carcinogenesis will yield important advances in diagnostics, prognostics, effective treatment, and outcome of oral cancer. Hence, in this study we have investigated the proteomic and peptidomic profiles by combining an orthotopic murine model of oral sq...

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Main Authors: Daniela C Granato, Mariana R Zanetti, Rebeca Kawahara, Sami Yokoo, Romênia R Domingues, Annelize Z Aragão, Michelle Agostini, Marcelo F Carazzolle, Ramon O Vidal, Isadora L Flores, Johanna Korvala, Nilva K Cervigne, Alan R S Silva, Ricardo D Coletta, Edgard Graner, Nicholas E Sherman, Adriana F Paes Leme
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4032327?pdf=render