Research of the Methylation Status of miR-124a Gene Promoter among Rheumatoid Arthritis Patients

Objective. To analyze the methylation status of miR-124a loci in synovial tissues of rheumatoid arthritis (RA) patients using methylation-specific polymerase chain reaction (MSP). Materials and Methods. DNA obtained from the frozen tissue of 7 RA samples, 6 osteoarthritis (OA) samples, and 3 healthy...

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Bibliographic Details
Main Authors: Qiao Zhou, Li Long, Guixiu Shi, Jing Zhang, Tong Wu, Bin Zhou
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2013/524204