Tiansi Liquid Modulates Gut Microbiota Composition and Tryptophan–Kynurenine Metabolism in Rats with Hydrocortisone-Induced Depression

Tiansi Liquid Modulates Gut Microbiota Composition and Tryptophan–Kynurenine Metabolism in Rats with Hydrocortisone-Induced Depression

Tiansi Liquid is a traditional Chinese herbal medicine used to treat depression; however, the underlying mechanisms remain unclear. Here, we examined the effect of Tiansi Liquid in a rat model of hydrocortisone-induced depression using behavioral testing, 16S rRNA high-throughput pyrosequencing and...

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Bibliographic Details
Main Authors: Dan Cheng, Hongsheng Chang, Suya Ma, Jian Guo, Gaimei She, Feilong Zhang, Lingling Li, Xinjie Li, Yi Lu
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
Tiansi Liquid
antidepressant effects
16S rRNA high-throughput pyrosequencing
gut microbiota
high-performance liquid chromatography-mass spectrometry
tryptophan–kynurenine pathway
Online Access:https://www.mdpi.com/1420-3049/23/11/2832

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https://www.mdpi.com/1420-3049/23/11/2832

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