CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus.

CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus.

Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. Viral receptor utilization is a major determinant of cell tropism, host range, and pathogenesis. The bona fide receptor for HNoV is unknown. Recently, we identified CD300lf as a proteina...

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Bibliographic Details
Main Authors: Vincent R Graziano, Forrest C Walker, Elizabeth A Kennedy, Jin Wei, Khalil Ettayebi, Madison S Strine, Renata B Filler, Ebrahim Hassan, Leon L Hsieh, Arthur S Kim, Abimbola O Kolawole, Christiane E Wobus, Lisa C Lindesmith, Ralph S Baric, Mary K Estes, Robert C Orchard, Megan T Baldridge, Craig B Wilen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008242

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https://doi.org/10.1371/journal.ppat.1008242

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